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This article appears in Surgical Endoscopy, Vol. 16, No. 6, June 2002 pgs. 931-935 This is the official journal of The Society of American Gastrointestinal Endoscopic
Surgeons (SAGES)
Dr. Fazzio was invited to present this paper in person at the annual meeting of SAGES in Atlanta in 1999 and at the World Congress of Endoscopic Surgery in Singapore in 2000
Cost Effective, Reliable Laparoscopic Hernia Repair A Report on 500 Consecutive Repairs F. J. Fazzio, Jr. Department of Surgery, St. Alphonsus Regional Medical Center, and Treasure Valley Hospital, Boise, ID 83706 USA Abstract Background: A series of 500 consecutive laparoscopic hernia repairs, performed by one surgeon, was undertaken to evaluate the procedure for reliability, safety, and cost-effectiveness. Methods: Patients with routine, first time, recurrent or multiply recurrent, inguinal hernias were operated using the technique described. Results: The recurrence rate was 0.2%. The complication rate was 0.6%. There were no deaths. 96% of patients returned to work in 4-10 days. Conclusions: Laparoscopic inguinal hernia repair is reliable, safe, and cost-effective. Key Words: Hernia Repair – Laparoscopy – Complications – Recurrence - Cost Effective
Unlike laparoscopic cholecystectomy, Laparoscopic Inguinal Hernia Repair has been slow to gain acceptance among the rank and file of practicing surgeons in America. Reports of unacceptably high recurrence rates have made some shy away. The excess cost of the surgical procedure has given others cause to avoid the procedure. And the difficulty in mastering the technique has been a barrier to a great many. This report describes a series of 500 consecutive laparoscopic hernia repairs performed by a single surgeon. The technique used is described and the principles of a safe dissection and a sound repair are set forth. There were only three significant complications in this series and only one recurrence. Only two disposable instruments were used for each case. This series demonstrates that Laparoscopic Inguinal Hernia Repair (LIHR) can be a highly reliable, safe, and cost-effective alternative to traditional open repair. Materials & Methods Clinical Study Between the dates 1-1-92 and 1-1-98, 500 consecutive herniated groins in 408 consecutive patients were repaired using LIHR. The patients were all males, ranging in age from 18 to 85 years of age. Almost all had routine, first time, or recurrent hernias. Two patients had multiply recurrent hernias. As the series progressed, the technique was modified and refined. The first 72 cases were performed via the transabdominal approach. Because the author became aware of anecdotal reports of small intestinal obstruction after LIHR, the technique was changed to the totally extraperitoneal approach. The remaining 428 groins were all repaired using this technique. A single disposable Hassan-type 12mm cannula was used for each case (Ethicon – model 512B). A 4" x 6" piece of polypropylene mesh was used for each groin. A laparoscopic stapler was used to fix the mesh in place (Ethicon – model EMS). No other disposable supplies were utilized. Two sutures of 2/0 Ethibond were used to fix the Hassan cannula in place, and close the umbilical fascia, and one suture of 4/0 Vycril was used to close all the skin incisions. Three Band-Aids were used as dressings. Operative technique and postoperative care Patients are placed supine with both arms placed on armboards in the crucifixion position. A Foley catheter is placed in all patients after the induction of anesthesia. All abdominal hair from the mid-epigastrium to the base if the penis and from one anterior superior iliac spine to the other is removed. The skin of this same area is then prepped with povidone iodine and the patients are draped in the usual sterile fashion. The surgeon positions himself at the patient’s side, across from the side involved with the hernia. A 2-3 cm curvilinear incision is made at a point 1 cm below the inferior aspect of the umbilicus. Cautery dissection is carried down entering the rectus sheath of the affected side. A Hassan-type cannula is fixed to the fascia with two 2/0 Ethibond sutures and positioned posterior to the rectus muscle and anterior to the posterior rectus sheath. A laparoscope is introduced to confirm that the setup has been correctly placed. Then and only then is insufflation commenced. The patient is now repositioned in Trendelenberg. Using the laparoscope as a blunt dissecting tool, this space is then developed in an inferior direction, extending below the end of the posterior rectus sheath, all the way to the pubic bone. Care is taken to keep the plane of dissection posterior to the muscles and anterior to the peritoneum. Next, a nondisposable 10mm cannula is placed in the suprapubic midline, and another cannula of this type is placed midway between the first two, both through 1 – 2 cm transverse incisions. Using both 5mm and 10mm blunt graspers of a type used in laparoscopic cholecystectomy, this extraperitoneal plane is developed laterally to a point just lateral to and superior to the anterior, superior iliac spine on the affected side. The retropubic space is exposed for a distance of 3 cm from the superior aspect of the pubic bone. If present, a direct hernia is pulled back into the abdomen as it is progressively dissected from its attachments to the surrounding tissues in the inguinal canal. In any event, Cooper’s ligament is completely exposed from the pubic bone over to the point where the iliac vessels cross it, and the dissection proceeds posteriorly down to a point just exposing the obturator nerve, artery, and vein as they enter the obturator foramen. From the point of origin of the inferior epigastric artery, the posterior peritoneum is dissected from lateral to medial completely uncovering the iliac artery over to a point about where it is crossed by the ureter. The peritoneum is dissected off the iliac artery, but all fibroadipose tissue over this vessel is left in place. In this way there is no direct contact between the iliac artery, and the subsequently placed mesh, which will overly it. The vas deferens is encountered during this part of the dissection, and its web-like attachments are disrupted as well. From the posterior aspect of the internal ring, the posterior peritoneum is dissected off of the testicular artery and vein in a superior (cephalad) direction for a distance of about 2 - 3 inches. The posterior dissection thus ends along a diagonal line, parallel to the inguinal ligament, that begins at the point where the ureter crosses the iliac artery, and ends about 3 cm superior and 2cm posterior to the anterior, superior iliac spine. An indirect hernia, if present is pulled back into the abdomen before the posterior dissection over the testicular vessels is commenced, progressively freeing it from its attachments to the surrounding tissues of the inguinal canal as it comes. Great care is taken to separate the posterior wall of the hernia sac from the vas deferens, and the testicular vessels as this dissection progresses. No attempt is made to excise the sac. Let us now assume we are standing on the patient’s left, and we are repairing the right groin. A 4" x 6" piece of polypropylene mesh is trimmed to exactly 3.5" x 5.5". This size is a good fit for 97% of adult males, with only a few cases requiring a smaller piece. No cases required a piece larger than 4" x 6". The corners of the mesh are slightly rounded with a scissors. The mesh will be placed parallel to a line connecting the upper end of the symphysis pubis to the anterior, superior iliac spine. This will result in the upper left corner of the mesh extending across the midline of the anterior abdominal wall above the pubis. This upper left corner of the mesh is therefore aggressively trimmed to conform to the patient’s midline. The mesh is then introduced into the abdomen and positioned so that the left end is at the pubic symphysis and the right end is at or near the anterior, superior iliac spine. The posterior border of the mesh is positioned so that it covers over Cooper’s ligament and extends 3–4 cm posterior to it. In no case is the mesh allowed to rest so far infero-posterior in the pelvis that it overlies the obturator nerve. Otherwise, postoperative paresthesias might result. Two staples are used to fix the mesh to Cooper’s ligament. About 6 – 8 staples are then place along the perimeter to temporarily hold it in place. One or two are placed at the superior aspect of the pubic bone, and proceeding cephalad and then laterally, it is progressively stapled in place. No staples are placed posterior to the anterior, superior iliac spine to avoid injury to any of the nerves traversing this region (cutaneous nerves of the anterior thigh and lateral hip regions). From a point on Cooper’s ligament, all along the infero-posterior edge of the mesh, to a point at the anterior, superior iliac spine, no staples are placed. These are the areas where nerve injury can occur and staples in this location are not essential to the durability of the repair. The patient is now repositioned in the flat position, out of Trendelenberg. A grasper in the middle cannula is used to grasp the posterior peritoneum and elevate it and place it on top of (anterior to) the posterior mesh on the surface of the psoas muscle/testicular vessels. This is to insure that as this peritoneum descends, it will not start itself posterior to the mesh, lifting the mesh anteriorly, as it continues its descent downward, and end up going through the internal ring, completely undoing the repair. This simple maneuver is all that is required to avoid this, rather than making holes or slits in the mesh to place part of the mesh behind the testicular vessels. The insufflation tubing is then disconnected from the Hassan cannula and the insufflation is allowed to slowly escape, all the while observing the peritoneum and intraperitoneal content as they descend to insure that they fill the hollow of the mesh, pressing it against both the anterior and posterior abdominal walls. The crucial point here is to not allow the posterior mesh to be displaced anteriorly. Instruments and cannulae are then removed under direct vision and finally the laparoscope and its cannula, and all insufflation is evacuated. The umbilical fascia is then closed with two figure–of–eight sutures of 2/0 Ethibond, using the same sutures that were fixing the Hassan cannula. The skin incisions are then closed with interrupted buried dermal sutures of 4/0 Vycril. Each is infiltrated with several c.c.s of ¼% Sensorcaine with epinephrine for postoperative pain control. Band-Aids are applied. Patients are instructed to remove the Band-Aids on the first postoperative morning and shower without protecting the wounds. Further dressings are at the patient’s discretion. Patients are permitted to return to any type of physical activity of their choosing, without limitation, beginning on the first postoperative day. Specifically, no lifting restrictions are imposed. Patients are seen on the third postoperative day and again three weeks thereafter. Further visits are on an as–needed basis. Results The follow–up period was 6 years. During this period there was one bona fide recurrence which required re-operation. There were three complications. One patient bled from a cannula site and had to be admitted overnight for observation. Transfusions were not required. One patient developed a significant infection at the umbilical wound. This was treated with drainage and oral cephalosporins. His mesh did not become involved in the infection, and three years later he has not resurfaced with any sign of any continuing difficulty. One elderly gentleman with prostatism preop seemed to be voiding satisfactorily in the first few days after surgery but went on to develop complete urinary retention and urosepsis. He would not respond to conservative management and ultimately required a TURP. His hernia repair remains intact. There were no cases of dysesthesias in this series. Ninety six percent of patients not retired were back to work in 4–10 days and 98% within 14 days. Less than 2% required 3 weeks before returning to work. Self employed individuals returned the most promptly, with employees of large corporations taking longer, and government employees taking the longest. Lack of a desire to return to work combined with a bureaucracy at a large employer, rather than any physical infirmity, seemed to be the most prevalent cause of delay in return to work. Discussion The muscular fibers of the undersurface of the abdominal wall make poor anchors for small sutures or staples. The integrity of a hernia repair of any kind using polypropylene mesh depends on one of two situations. Either the mesh is firmly sutured to strong, fibro-ligamentous tissues or fascia around the margins of the defect, or the mesh must reside beneath the strength layers and be of sufficient size to widely overlap the defect. The latter case is the most prevalent situation in the inguinal region. It is the friction of the rough surface of the mesh, combined with its placement in a sandwich between layers of the abdominal wall that results in the immediate strength of this repair. While the laparoscopic approach adds a new dimension to this type of repair, it is really nothing more than a classic preperitoneal hernia repair, the reliability of which has been well known to surgeons for decades. Nyhus et al [1] and Stoppa [2] emphasized that the success of the repair is directly proportional to the size of the mesh relative to the size of the defect. Most current renditions of laparoscopic hernia repair rely on too small a piece of mesh. They further fail to recognize the reliability of the roughness of the surface of the mesh in preventing migration. This often results in the placement of an excessive number of staples in the mistaken belief that this will reliably secure the mesh. Neither the staples themselves, nor the majority of the tissues into which they are placed, are strong enough to protect the integrity of the repair. Furthermore, the tendency to over-staple increases the incidence of nerve injury. Nowhere is this more true than along the posterior aspect of the internal ring where nerve injuries are most common. Using a slit and keyhole in the mesh in an effort to fix it posteriorly has some merit. However, such a violation of the integrity of the mesh invites recurrences exactly at the internal ring where protection is most needed. Dissecting up onto the anterior surface of the psoas muscle and testicular vessels for a distance of 2–3 inches, and taking care to see that the mesh ends up posterior to the posterior peritoneum, results in the intra-abdominal organs resting in an intact "sling" of mesh. This sling begins on the anterior abdominal wall, proceeds down over the internal ring, and then courses back up on the posterior abdominal wall. The overall size of the mesh combined with its placement in this fashion are the two factors that are at the essence of the reliability of this repair. Traditional hernia repair by the anterior approach, with or without the use of mesh, and with all its iterations and variations, comes up short by comparison. All such repairs rely on the healing of approximated tissues for their success. The science of wound healing has taught us that this process requires six weeks to achieve the majority of its strength. Most surgeons will advise patients not to "test" their hernia repairs severely for six weeks for this reason. In contrast, the technique described herein approximates no tissues, but rather replaces missing or damaged tissues with a large "patch", much like "booting" a large hole inside a tubeless tire. As soon as the repair is complete, the patient is immediately ready to go back "out on the road", with only the resolution of postoperative pain being a barrier to immediate return to vigorous physical activity. As the mesh becomes incorporated into dense collagenous tissue over time, the repair only becomes ever stronger than it really needs to be. Surgeons have long witnessed the situation in which an indirect inguinal hernia repair is followed some years later by the presentation of the patient with a "recurrent" hernia. Upon re-exploration, the recurrence is found to be a direct hernia. The technique described herein prevents the occurrence of any future direct, indirect, or femoral hernias. Postoperative pain is minimized with this technique. This is especially so if the patient has bilateral inguinal hernias since both sides can be repaired through the same three cannulae. The surgeon merely stands on the opposite side of the operating table to repair the other side. When both sides are to be repaired initially, the preferred approach is to enter the preperitoneal space in the exact midline from the infraumbilical incision, rather than entering the rectus sheath on the side of a single hernia repair. Gaining access through the rectus sheath for a one-sided procedure, and confining the dissection to a point just short of reaching the midline all along the line from the umbilicus to the symphysis pubis, avoids scarring the midline. If the patient subsequently requires a repair of the opposite side, then the other rectus sheath, etc. will be "virgin" territory. The technique described herein is particularly well suited to the repair of recurrent hernias, originally repaired by the traditional anterior approach because of the difficulties in re-dissecting a previously operated groin. The postoperative pain for a redo traditional repair is substantially more than the first repair, and the risk of nerve injury is increased. Neither is true of the laparoscopic approach to the repair of a recurrent, traditionally repaired hernia. This reduced pain after LIHR, combined with early strength of the repair, results in early return to work. This parallels reports by others [3, 4, 5, 6]. Studies have reported typical recurrence rates for conventional hernia repair of 10-15% [7, 8]. This is consistent with the fact that 15% of all hernia repairs are recurrent hernia repairs [9]. Happily, the author has little experience in repairing recurrence after the laparoscopic approach described herein. The single recurrence in this series occurred at about the 100 th case. No reasonable method of traversing the previously dissected planes could be conjured up preoperatively at the time of the second repair. Therefore the repair was approached traditionally. This may be one of the few disadvantages of the laparoscopic approach, although if the rate of recurrence is kept this low, it is a relatively theoretic disadvantage. At surgery, this patient was found to have recurred because the posterior aspect of the mesh had been displaced anteriorly. In other words, the mesh was folded upon itself with both halves up against the anterior abdominal wall and the fold at the internal ring. Both the anterior abdominal peritoneum and the posterior abdominal peritoneum were posterior to the mesh, thus allowing free access of the peritoneum and intraperitoneal contents to the internal ring. An analysis of this failure resulted in changing the technique slightly to prevent its repetition and no such occurrence has been witnessed in the subsequent 400 cases. This could only occur at the end of the case, when the instruments are removed and the insufflation evacuated. Good laparoscopic technique mandates that the instruments and cannulae are removed under direct vision. This implies that insufflation is present as they are removed. As the insufflation is released and exits the abdomen, and the posterior peritoneum descends, if it catches the upper border of the posterior mesh and displaces it inferiorly and anteriorly, this may not be seen. The technique was modified in the following way. The laparoscope is kept in place through the umbilical port. The point on the peritoneum that corresponds to the posterior aspect of the internal ring is grasped with a 5-mm grasper through the middle port and elevated over the top of the posterior mesh. It is then placed down on top of the mesh and held in place at the internal ring while the suprapubic cannula is removed, and the insufflation tubing is disconnected from the umbilical cannula. As the gas exits the abdomen, the intraperitoneal contents are observed to descend and fill the peritoneum. They come to rest on top of the posterior peritoneum, as desired. The grasper, laparoscope and both cannulae are then slowly and carefully removed. If any resistance to their removal is met, the insufflation tubing is reconnected and the abdomen refilled to see what the problem might be. This technique has resulted in a recurrence free experience since it was adopted.A frequent occurrence is the development of a seroma in the inguinal canal. This occurs because blood and serum from the preperitoneal dissection can accumulate in the first few hours after surgery and pass directly through the mesh, entering the potential space left in the inguinal canal as a result of having removed the hernia and placed it back in the abdomen. Further, blood and serum originating from the inguinal tissues themselves, as a result of dissecting the hernia free from them, can accumulate here as well. Such collections are usually small but can appear to be a recurrence initially. However, if one is not aggressive about re-exploring such a groin, one will find that the mass becomes smaller, firmer, and ultimately disappears completely with the passage of time. Most often the presence of a seroma is not even noticed by the patient. Seldom is it a source of symptoms.Cord lipomas, if identifiable, are pulled back into the abdomen and completely removed. Occasionally they are pulled back into the abdomen and then placed anterior to the posterior mesh and left there. If there is one aspect of laparoscopic repair that is not entirely satisfactory it is the business of dealing with cord lipomas. If not detected and removed, a subsequent examiner may mistake them for recurrent hernias. In addition, dissection of a large cord lipoma often results in a clear hematoma/seroma in the inguinal canal postoperatively. While this is initially of concern to the patient, it has not proven to cause a delay in return to activity and work. Vascular injury to the iliac or inferior epigastric vessels, trocar site hernia, hydrocoele, nerve injury, urinary retention, testicular atrophy, and wound infection are some of the complications that have been reported with both conventional and laparoscopic repair [8, 10]. Conventional hernia repair carries with it a typically reported complication rate of 10% [10]. In this series there were but three complications, for a rate of 0.6%. One patient bled from a cannula site. His hematocrit fell by over 10%. He was observed overnight and did not require transfusion. At this stage in the series, a unilateral hernia was repaired through three cannulae, with one at the umbilicus, one at a point three inches cephalad to the anterior, superior iliac spine, and a third midway between the first two. It was the middle cannula that bled. This technique had the added disadvantage of requiring a total of five cannulae to repair bilateral hernias. The technique was modified to incorporate the use of only three cannulae in the midline. This saved the patients the pain of two additional ports and there were no subsequent occurrences of bleeding. One patient developed a rather significant and purulent umbilical infection. The umbilicus is notorious for harboring many bacteria. It is perhaps surprising that more infections did not occur. An emphasis on deep scrubbing and prepping the umbilicus prior to commencing the procedure is all that can be done about this. This patient did not develop a mesh infection. One elderly gentleman developed urinary retention, urosepsis, and required TURP before the problem would resolve. He had symptoms of prostatism preoperatively, but had declined to have surgical intervention. It is easy to conclude that all such patients should have their prostatic obstruction relieved before hernia surgery is performed. Such a condition is cited among the causes of recurrent hernia. While this is undeniably true, the practical aspects of dealing with patient-customers can often interfere with sound surgical principles. How often are surgeons successful in convincing patients who are to have traditional hernia repair for bilateral hernias, that they would be better served to have one side repaired, and wait six weeks before repairing the other side? Conclusion Laparoscopic hernia repair is a superior approach to the problem of inguinal hernia. Lengthy operative time, unacceptably high recurrence rates, and occasional serious complications can result in a lack of enthusiasm for the procedure. The technique is also difficult to master. However, when properly performed it can be safe, reliable, and quite cost-effective. While difficult to measure, the ability to return to work much sooner results in an immense savings in lost productivity, the cost of temporary replacement employees, and unemployment compensation funds. Eliminating all the costs involved in repairing 10-15% recurrent hernias is also an extraordinary saving. References 1. Nyhus LM, Condon RE. Hernia. Third edition. Philadelphia,PA: J.B.Lippencott Company, 1989: 205-206 2. Stoppa RE. The treatment of complicated groin and incisional hernias. World J Surgery; 13:545-554. 3. Liem MSL, et al. Comparison of Conventional Anterior Surgery and Laparoscopic Surgery for Inguinal Hernia Repair. NEJM 1997; 336: 1541-1547. 4. Payne JH Jr, et al. Laparoscopic or open inguinal herniorrhaphy? A randomized prospective trial, Arch Surg 1994; 129: 979-981 5. Vogt DM, et al. Preliminary results of a prospective randomized trial of laparoscopic only versus conventional inguinal herniorrhaphy. Am J Surg 1995; 169: 84-90. 6. Liem MSL, et al. A randomized comparison of physical performance following laparoscopic and open inguinal hernia repair. Br J Surg 1997; 84: 64-67. 7. Rand Corp: Conceptualization and Measurement of Physiologic Health for Adults. Santa Monica, CA, Rand Corp Publication 15,1983, p 3 8. Nyhus LM, Condon RE. Hernia. Fourth edition. Philadelphia,PA: J.B.Lippencott Company, 1995: 253-268. 9. Morfesis FA. The Recurrence rate in hernia surgery. Arch Surg 1996; 131: 107 10. Miguel PR, et al. Laparoscopic hernia repair – complications. JSLS 1998; 2: 35-40
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